The suppressor of cytokine signaling (SOCS) (e.g. SOCS1 and SOCS3) are considered the most potent negative regulators used by cells to control type I IFN signaling as they can directly interact with TYK2 interfering with its activation. (33362795)
The suppressor of cytokine signaling (SOCS) (e.g. SOCS1 and SOCS3) are considered the most potent negative regulators used by cells to control type I IFN signaling as they can directly interact with TYK2 interfering with its activation. (26061044)