HAS2-AS1 (non-coding RNA) == binding ==> HAS2 (Gene)

HAS2-AS1 is necessary for the transcription of its sense counterpart HAS2 upon hypoxia treatment. HAS2-AS1 is up-regulated in OSCC tissues compared with normal tissue. In addition, hypoxia induces the expression of HAS2-AS1 in OSCC cells in an HIF-1α dependent manner. Moreover, HAS2-AS1 is essential for the transcription of HAS2, thereby mediating the hypoxia-induced invasiveness of OSCC cells (28485478)

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