ATXN3 (Protein) == deubiquitination ==> PARK2 (Protein)

Ataxin-3 regulates the ability of parkin to ubiquitinate itself, with Ataxin-3 decreasing parkin self-ubiquitination. Moreover, mutant type Ataxin-3 promotes the clearance of parkin via the autophagic degradation of parkin. (32982735)

Pubmeds: