MIR21 (5p microRNA) == microRNA binding ==> TIMP3 (mRNA)

miR-21 may be involved in the tumorgenesis of ESCC by targeting FASL, TIMP3 and RECK. (23504349)
"HMGB1-miR-21 signaling cascade promotes tumor progression by repression of the MMP inhibitors, RECK and TIMP3..." (25720799)

Pubmeds: