ONCO.IO

ONCO.IO is an integrative resource for microrna and transcription factors analysis in cancer.

Network analysis tools Build network by filter
DB updated every two week
last update: FOS=>SOX9, 2017-06-26 23:56:49 by Rhizoman1

ONCO.IO is an integrated knowledge database and network analysis tool for exploring complex gene regulatory networks involved in cancer.

ONCO.IO database content is based on the manually curated annotation of experimentally verified molecular interactions described in the literature and includes microRNAs, lncRNAs, mRNAs, signaling proteins and transcription factors interactions.

Key features:

ONCO.IO statistics

Total number of interactions:
12091

binding of miRNA:
4161

transcription regulation:
3633

drug interactions:
454

chemo/drugresistance:
175

metabolic reactions:
8207

TF => ncRNA reactions:
531

drug => gene/miR reactions:
454
Path. processes associations:
7823

Diseases associations:
6032

Pubmeds:
13991

Express.levels associations:
2322

Prognosis associations:
682

Diagnosis associations:
47

Biomarker localization:
1854

Cell lines associations:
12170

Tumor stage associations:
54

Methods associations:
29704

Cell Localization:
396
number of new added interactions:
for last week:
5
(
-33
)
for last 2 weeks:
43

for last month:
184 (
-151
)

for last two month:
519

top annotators of last month:
Rhizoman1:
159
(
-111
)
Вася:
1
(
+1
)
shapych:
22
(
-36
)
admin:
1
(
+1
)
Rayvel:
1
(
+1
)

Last added links: FOS=>SOX9 MIR145=>CD40 HMGA1=>ABCG2 NANOG=>BNIPL SOX2=>CD274


Long non-coding RNA interactions page

Search term and build network:


Processes

Pathogenic process (PP) - molecular, cellular or tissue malfunction determining initiation, development and outcome of disease. Full list of PP is here
Interactions (or edges) are associated with pathogenic process and can influence as positively and negatively on the process.

Processes:

Diseases

Diseases:

Genes and ncRNAs

Symbol:

Or use more complex filters.

News:

Mobile devices bug fixes: single and double tap is working now 27 June 2017 13:45:25 by Sasha Fokin
This week we are going to annotate SOXs transcription factors in various cancers! 19 June 2017 16:15:47 by rhizoman1
Days of colorectal cancer! 10 June 2017 00:30:42 by rhizoman1
New day with miR-335 - adding cancer relations! 05 June 2017 14:53:27 by rhizoman1
New regulatory interactions in Prostate cancer (PCa) 03 June 2017 15:45:31 by rhizoman1
miR-424 has many faces in cancer biology! 30 May 2017 21:16:18 by rhizoman1
Hello! We are adding new association Mirs in PCa 29 May 2017 22:25:26 by rhizoman1
We are starting! 26 May 2017 23:26:52 by rhizoman1
Simple news feed (blog) about onco.io development. 26 May 2017 15:32:02 by Sasha Fokin
Blog

Last saved networks:

miRNA network mir205 mir101-1 [27 June 2017 13:06:36 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
parent=>filter 3 [26 June 2017 20:57:20 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
Prostate cancer + cisplatin resistance [23 June 2017 15:01:53 by Sasha Fokin -- 87.245.153.236 / RUSSIAN FEDERATION]
g_test1 [11 June 2017 18:59:25 by guest -- 46.188.123.187 / unknown]
Colodectal and metastasis [10 June 2017 00:59:31 by guest -- 46.188.123.187 / unknown]
multifilter parent test [07 June 2017 14:42:56 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
HCC, Apoptosis, Invasion in tumor, only microRNA bindin mechanizm. Filter origin test [07 June 2017 14:41:25 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
parent=>filter=>next [07 June 2017 01:05:53 by Sasha Fokin -- 46.188.123.187 / unknown]
parent=>filter [07 June 2017 01:04:33 by Sasha Fokin -- 46.188.123.187 / unknown]
parent5=>6=>7 [07 June 2017 01:02:06 by Sasha Fokin -- 46.188.123.187 / unknown]
All saved networks


Coming soon:


Metabolites

Pubmeds

Drugs

Interactions

Mutations

Educational game