ONCO.IO

ONCO.IO is an integrative resource for microrna and transcription factors analysis in cancer.

Network analysis tools Build network by filter
DB updated every two week
last update: MIR140=>ITPKB, 2017-09-21 13:35:51 by rhizoman1

ONCO.IO is an integrated knowledge database and network analysis tool for exploring complex gene regulatory networks involved in cancer.

ONCO.IO database content is based on the manually curated annotation of experimentally verified molecular interactions described in the literature and includes microRNAs, lncRNAs, mRNAs, signaling proteins and transcription factors interactions.

Key features:

ONCO.IO statistics

Total number of interactions:
12269

binding of miRNA:
4264

transcription regulation:
3681

drug interactions:
454

chemo/drugresistance:
178

metabolic reactions:
8207

TF => ncRNA reactions:
539

drug => gene/miR reactions:
454
Path. processes associations:
8174

Diseases associations:
6170

Pubmeds:
14196

Express.levels associations:
2378

Prognosis associations:
724

Diagnosis associations:
48

Biomarker localization:
1944

Cell lines associations:
12494

Tumor stage associations:
54

Methods associations:
30767

Cell Localization:
396
number of new added interactions:
for last week:
26
(
-40
)
for last 2 weeks:
92

for last month:
119 (
+105
)

for last two month:
133

top annotators of last month:
rhizoman1:
119
(
+106
)

Last added links: MIR140=>ITPKB MIR195=>GABARAPL1 MIR30E=>BECN1 MIR4520A=>RHEB E2F1=>MAP1LC3B


Long non-coding RNA interactions page

Search term and build network:


Processes

Pathogenic process (PP) - molecular, cellular or tissue malfunction determining initiation, development and outcome of disease. Full list of PP is here
Interactions (or edges) are associated with pathogenic process and can influence as positively and negatively on the process.

Processes:

Diseases

Diseases:

Genes and ncRNAs

Symbol:

Or use more complex filters.

News:

Autophagy interactome: microRNA, TFs and protein-protein interactions 24 August 2017 22:08:25 by rhizoman1
We will continue to adding Interactions involved in cancer! 14 August 2017 20:37:45 by rhizoman1
EMT as complex process involved in drug resistance and stemness! 27 July 2017 02:23:48 by rhizoman1
Sox4 as an EMT regulator! 16 July 2017 03:20:01 by rhizoman1
Pancreatic cancer! 01 July 2017 01:28:01 by rhizoman1
Mobile devices bug fixes: single and double tap is working now 27 June 2017 13:45:25 by Sasha Fokin
This week we are going to annotate SOXs transcription factors in various cancers! 19 June 2017 16:15:47 by rhizoman1
Days of colorectal cancer! 10 June 2017 00:30:42 by rhizoman1
New day with miR-335 - adding cancer relations! 05 June 2017 14:53:27 by rhizoman1
New regulatory interactions in Prostate cancer (PCa) 03 June 2017 15:45:31 by rhizoman1
Blog

Last saved networks:

TF_autophagy_13_09 [13 September 2017 16:15:28 by guest -- 176.193.187.192 / unknown]
TF regulation_autophagy [08 September 2017 16:53:11 by guest -- 176.193.187.192 / unknown]
autophagy_08_09 [08 September 2017 12:57:48 by guest -- 176.193.187.192 / unknown]
mahsa [03 September 2017 13:20:28 by guest -- 217.146.218.171 / ISLAMIC REPUBLIC OF IRAN]
[09 August 2017 08:12:11 by guest -- 54.165.59.7 / UNITED STATES]
network [09 July 2017 12:21:34 by guest -- 217.146.218.171 / ISLAMIC REPUBLIC OF IRAN]
miRNA network mir205 mir101-1 [27 June 2017 13:06:36 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
parent=>filter 3 [26 June 2017 20:57:20 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
Prostate cancer + cisplatin resistance [23 June 2017 15:01:53 by Sasha Fokin -- 87.245.153.236 / RUSSIAN FEDERATION]
g_test1 [11 June 2017 18:59:25 by guest -- 46.188.123.187 / unknown]
All saved networks


Coming soon:


Metabolites

Pubmeds

Drugs

Interactions

Mutations

Educational game