ONCO.IO

ONCO.IO is an integrative resource for microrna and transcription factors analysis in cancer.

Network analysis tools Build network by filter

DB updated every two week
last update: FOS=>SOX9, 2017-06-26 23:56:49 by Rhizoman1

ONCO.IO is an integrated knowledge database and network analysis tool for exploring complex gene regulatory networks involved in cancer.

ONCO.IO database content is based on the manually curated annotation of experimentally verified molecular interactions described in the literature and includes microRNAs, lncRNAs, mRNAs, signaling proteins and transcription factors interactions.

Key features:

ONCO.IO statistics

Total number of interactions:
12091

binding of miRNA:
4161

transcription regulation:
3633

drug interactions:
454

chemo/drugresistance:
175


metabolic reactions:
8207

TF => ncRNA reactions:
531

drug => gene/miR reactions:
454


Path. processes associations:
7823

Diseases associations:
6032

Pubmeds:
13991

Express.levels associations:
2322

Prognosis associations:
682

Diagnosis associations:
47

Biomarker localization:
1854

Cell lines associations:
12170

Tumor stage associations:
54

Methods associations:
29704

Cell Localization:
396

number of new added interactions:
for last week:
5
(
-33
)
for last 2 weeks:
43

for last month:
184 (
-151
)

for last two month:
519


top annotators of last month:
Rhizoman1:
159
(
-111
)
Вася:
1
(
+1
)
shapych:
22
(
-36
)
admin:
1
(
+1
)
Rayvel:
1
(
+1
)


Search term and build network:


Processes

Pathogenic process (PP) - molecular, cellular or tissue malfunction determining initiation, development and outcome of disease. Full list of PP is here
Interactions (or edges) are associated with pathogenic process and can influence as positively and negatively on the process.

Processes:

Diseases

Diseases:

Genes and ncRNAs

Symbol:



Last saved networks:

miRNA network mir205 mir101-1 [27 June 2017 13:06:36 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
parent=>filter 3 [26 June 2017 20:57:20 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
Prostate cancer + cisplatin resistance [23 June 2017 15:01:53 by Sasha Fokin -- 87.245.153.236 / RUSSIAN FEDERATION]
g_test1 [11 June 2017 18:59:25 by guest -- 46.188.123.187 / unknown]
Colodectal and metastasis [10 June 2017 00:59:31 by guest -- 46.188.123.187 / unknown]
multifilter parent test [07 June 2017 14:42:56 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
HCC, Apoptosis, Invasion in tumor, only microRNA bindin mechanizm. Filter origin test [07 June 2017 14:41:25 by guest -- 87.245.153.236 / RUSSIAN FEDERATION]
parent=>filter=>next [07 June 2017 01:05:53 by Sasha Fokin -- 46.188.123.187 / unknown]
parent=>filter [07 June 2017 01:04:33 by Sasha Fokin -- 46.188.123.187 / unknown]
parent5=>6=>7 [07 June 2017 01:02:06 by Sasha Fokin -- 46.188.123.187 / unknown]

All saved networks



Coming soon:


Metabolites

Pubmeds

Drugs

Interactions

Mutations

Educational game